What is it: Trichloroacetic Acid

What is Trichloroacetic Acid?

Trichloroacetic acid (TCA) is a chemical compound that belongs to the family of carboxylic acids. Its molecular formula is C2HCl3O2 and its molar mass is approximately 163.39 g/mol. TCA is a strong, highly corrosive, water-soluble acid.

Physical and chemical properties of Trichloroacetic Acid

Trichloroacetic acid is a colorless or white liquid with a characteristic odor. Its density is approximately 1.63 g/cm³ and its melting point is approximately 55 °C. TCA is highly volatile and has a boiling point of around 196°C.

TCA is a strong acid, which means it is capable of donating protons (H+ ions) in aqueous solution. This characteristic makes trichloroacetic acid highly corrosive and capable of causing burns to the skin and eyes. Furthermore, TCA is a monoprotic acid, that is, it has only one acidic group that can donate a proton.

Uses of Trichloroacetic Acid

Trichloroacetic acid has a wide range of applications in different areas. One of the main uses of TCA is in the pharmaceutical industry, where it is used as a cauterizing and skin exfoliating agent. TCA is also used in the synthesis of organic compounds, in the production of dyes and in the plastics industry.

Furthermore, trichloroacetic acid is used in the analysis of proteins, being a commonly used reagent to precipitate proteins in solution. This property of TCA is widely used in molecular biology and biochemistry laboratories.

Effects of Trichloroacetic Acid on human health

Trichloroacetic acid is highly corrosive and can cause serious harm to human health. Direct contact with the skin can cause chemical burns, irritation and redness. Additionally, TCA can cause damage to the eyes, resulting in irritation, redness, pain, and even serious injury.

If trichloroacetic acid is ingested or inhaled, systemic effects may occur, such as nausea, vomiting, abdominal pain, dizziness, difficulty breathing and even damage to the liver and kidneys. It is important to highlight that TCA is a dangerous chemical and its handling must be done with extreme caution, using appropriate personal protective equipment.

Precautions when handling Trichloroacetic Acid

Due to its corrosive and toxic nature, it is essential to take appropriate precautions when handling trichloroacetic acid. It is recommended to use protective gloves, safety glasses and a protective apron when dealing with TCA. Furthermore, it is important to work in a well-ventilated area or use respiratory protection equipment if there is a risk of inhaling the acid.

In case of contact with the skin, it is essential to immediately wash the affected area with plenty of water and seek medical attention. In case of contact with the eyes, it is necessary to wash them with running water for at least 15 minutes and seek immediate medical assistance.

Final thoughts on Trichloroacetic Acid

Trichloroacetic acid is a chemical compound with corrosive and toxic properties. Its use must be carried out with extreme caution, following appropriate safety precautions. It is important to highlight that TCA is a dangerous chemical product and must be handled by trained and properly equipped professionals.

This glossary aimed to provide detailed information about trichloroacetic acid, its physical and chemical properties, uses, effects on human health and precautions in handling. It is essential to be aware of the risks associated with this chemical compound and adopt appropriate safety measures when dealing with TCA.

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